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2

Synthetic lethality offers a new approach to kill tumor cells, explains Moffitt researcher

from Eurekalert - 31 Oct 14

(H. Lee Moffitt Cancer Center & Research Institute) The scientific community has made significant strides in recent years in identifying important genetic contributors to malignancy and developing therapeutic agents that target altered genes and proteins. A recent approach to treat cancer called synthetic lethality takes advantage of genetic alterations in cancer cells that make them more susceptible to certain drugs. Alan F. List, MD, president and CEO of Moffitt Cancer Center, co-authored an



2

Sexual fantasies: Are you normal?

from Eurekalert - 31 Oct 14

(University of Montreal) Hoping for sex with two women is common but fantasizing about golden showers is not. That's just one of the findings from a research project that scientifically defines sexual deviation for the first time ever.



2

Scientists trigger self-destruct switch in lung cancer cells

from Cancer Research News - 31 Oct 14

Press release Cancer Research UK scientists have found a drug combination that can trigger the self-destruct process in lung cancer cells - paving the way for new treatments, according to research that will be presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool next week*. “Igniting the fuse that causes lung cancer cells to self-destruct could pave the way to a completely new treatment approach." - Professor Henning Walczak. When healthy cells are no longe



2

How "trained immunity" mediates BCG therapy of bladder cancer

from MNToncology - 30 Oct 14

Bacillus Calmette-Guerin (BCG) is a vaccine widely used in low and middle-income countries to protect against childhood tuberculosis.



2

Navigation and location can occur without external cues

from MNTneuro - 30 Oct 14

Researchers from The University of Queensland have identified the amount of information the brain needs in order to navigate and accurately estimate location.



2

Subarachnoid hemorrhage induces an early and reversible cardiac injury associated with catecholamine release: one-week follow-up study

from Critical Care Forum - 30 Oct 14

IntroductionThe occurrence of cardiac dysfunction is common after subarachnoid haemorrhage (SAH) and was hypothesized to be related to the release of endogenous catecholamines. The aim of this prospective study was to evaluate the relationship between endogenous catecholamine and cardiac dysfunction at the onset and during the first week after SAH. Methods: Forty consecutive patients admitted for acute SAH without known heart disease were included. Catecholamine plasma concentrations and transth



2

Scientists grow a miniature human stomach from stem cells

from MNTgastro - 30 Oct 14

Researchers have grown fully functioning, miniature human stomachs from stem cells, providing a model in which to study diseases such as stomach cancer and metabolic syndrome.



2

Personalised IVF care at Malpani Infertility Clinic

from Dr and Patient - 31 Oct 14

•    We will try not to make you feel rushed when we meet with you. Yes, we are busy, but when we are seeing you, you are the focus of our attention !•    We will try to make you feel comfortable , so that you feel free to ask any question you like. We will do our best to clear all your doubts, so that you never feel that any of your questions are stupid•    We will respect your preferences and allow you to make your own decisions . We will treat you



2

Text messaging could motivate Latino adults to exercise

from MNTcvs - 30 Oct 14

Latino adults at risk of heart disease exercise more after receiving motivational text messages five days a week, a pilot study suggests.Peripheral arterial disease (PAD) affects 13.



2

Heart failure linked to gut bacteria compound

from MNTcvs - 30 Oct 14

New study finds that risk of death from heart failure in patients with the condition is linked to levels of the compound TMAO - a byproduct of gut bacteria - in their blood.



2

Nano ruffles in brain matter

from MNTdementia - 30 Oct 14

An accumulation of a protein called amyloid-beta into large insoluble deposits called plaques is known to cause Alzheimer's disease.



2

Expectant mothers with epilepsy face tough choices over their medication

from MNTepilepsy - 30 Oct 14

A new study published in The Cochrane Library, highlights the difficult decisions women with epilepsy have to face when they become pregnant.



2

Risk of ruptured appendix for young children increased by poor access to general surgeons

from MNTgastro - 30 Oct 14

Delayed treatment for appendicitis can often lead to a ruptured appendix. That's exactly what is more likely to happen to many children in North Carolina if they have to delay getting treatment...



2

Low-carb, high-fat diets may reduce epilepsy seizures

from MNTcvs - 30 Oct 14

Scientists find that diets high in fat and low in carbohydrates, such as the ketogenic diet or modified Atkins diet, may reduce seizures in adults with refractory epilepsy.



2

Clinical practice guidelines address multimodality treatment for esophageal cancer

from MNToncology - 30 Oct 14

The Society of Thoracic Surgeons (STS) has released new clinical practice guidelines for treating cancer of the esophagus and gastroesophageal junction (area where the esophagus meets the stomach).



2

New technology shows promise for delivery of therapeutics to the brain

from MNToncology - 30 Oct 14

A new technology that may assist in the treatment of brain cancer and other neurological diseases is the subject of an article in a recent issue of the journal Technology, published by World...



2

Aortic valve replacement appears safe, effective in very elderly patients

from MNTcvs - 30 Oct 14

Aortic valve replacement (AVR) can safely be used to treat severe aortic stenosis in patients age 90 years and older and is associated with a low risk of operative stroke and mortality, according...



2

Health experts: perfect storm of diabetes and tuberculosis must be headed off

from MNTdiabetes - 30 Oct 14

The International Union Against Tuberculosis and Lung Disease (The Union) and the World Diabetes Foundation have released a report calling for international action against a looming co-epidemic of...



2

Risk of poor outcomes in elderly patients predicted by new frailty test

from MNTarthritis - 30 Oct 14

A simplified frailty index created by surgeons at Wayne State University School of Medicine in Detroit, Mich.



2

Solution to 14-year mystery has implications for cancer therapies and drug delivery

from MNToncology - 30 Oct 14

Do blood vessels that feed tumors differ from other blood vessels? Fourteen years ago, experiments designed to answer that question led to the discovery of several genes that are more active in...



2

Improved understanding of glioma may lead to more efficient and specific therapies

from MNToncology - 30 Oct 14

Glioma is a common name for serious brain tumours. Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain.



2

Improved understanding of glioma may lead to more efficient and specific therapies

from MNToncology - 30 Oct 14

Glioma is a common name for serious brain tumours. Different types of glioma are usually diagnosed as separate diseases and have been considered to arise from different cell types in the brain.



2

Finding could lead to treatments for channel-related diseases such as cardiac arrhythmias, epilepsy and Parkinson's

from MNTcvs - 30 Oct 14

A common protein plays a different role than previously thought in the opening and closing of channels that let ions flow in and out of our cells, researchers at Johns Hopkins report.



2

Pediatric radiation exposure following Chernobyl disaster linked to aggressive thyroid cancers

from MNToncology - 30 Oct 14

For the first time, researchers have found that exposure to radioactive iodine is associated with more aggressive forms of thyroid cancer, according to a careful study of nearly 12,000 people in...



2

Women more likely than men to dismiss chest pain and delay seeking medical help for heart symptoms

from MNTcvs - 30 Oct 14

When heart symptoms strike, men and women go through similar stages of pain but women are more likely to delay seeking care and can put their health at risk, according to a study presented at the...


 

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