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Gene 'switches' could predict when breast cancers will spread to the brain

from Cancer Research News - 05 Nov 14

Press release Scientists have found a pattern of genetic ‘switches’ – chemical marks that turn genes on or off - that are linked to breast cancer’s spread to the brain, according to research* presented at the National Cancer Research Institute Cancer Conference in Liverpool today (Wednesday). "Tackling the problem of brain metastases is one of the greatest challenges facing breast cancer researchers" - Dr Abeer Shaaban The researchers, based at the University of Wolverhampton, studied 24 breas


Ethical Considerations Surrounding Lethal Injection

from JAMA - 05 Nov 14

To the Editor Perhaps no part of the criminal justice system is more fraught with moral, ethical, and legal dilemmas than the execution process. The paramount concern of the Death Penalty Committee of The Constitution Project was to ensure that the system is as fair and transparent as possible and comports with the numerous protections found in the US Constitution. As Dr Truog and colleagues pointed out, the Committee of The Constitution Project found that the justice system fails to do this in


Sepsis-related deaths in Brazil: an analysis of the national mortality registry from 2002 to 2010

from Critical Care Forum - 05 Nov 14

IntroductionLimited population-based epidemiologic information about sepsis? demography, including its mortality and temporal changes is available from developing countries. We investigated the epidemiology of sepsis deaths in Brazil using secondary data from the Brazilian Mortality Information System. Methods: Retrospective descriptive analysis of Brazilian multiple-cause-of-death data between 2002 and 2010, with sepsis-associated International Classification of Diseases, 10th Revision (ICD-10)


Solution to 14-year mystery has implications for cancer therapies and drug delivery

from MNToncology - 30 Oct 14

Do blood vessels that feed tumors differ from other blood vessels? Fourteen years ago, experiments designed to answer that question led to the discovery of several genes that are more active in...


Scientists trigger self-destruct switch in lung cancer cells

from Cancer Research News - 31 Oct 14

Press release Cancer Research UK scientists have found a drug combination that can trigger the self-destruct process in lung cancer cells - paving the way for new treatments, according to research that will be presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool next week*. “Igniting the fuse that causes lung cancer cells to self-destruct could pave the way to a completely new treatment approach." - Professor Henning Walczak. When healthy cells are no longe


Researchers discover type of toxic flame retardant in Americans for first time

from MNToncology - 15 Nov 14

By finding a way to test urine for phosphate biomarkers, researchers have identified a previously undiscovered toxic flame retardant - TCEP - in Americans.


Scientists grow a miniature human stomach from stem cells

from MNTgastro - 30 Oct 14

Researchers have grown fully functioning, miniature human stomachs from stem cells, providing a model in which to study diseases such as stomach cancer and metabolic syndrome.


Stem cells that release cancer-killing toxins offer new brain tumor treatment

from MNToncology - 27 Oct 14

Scientists have made stem cells that produce and secrete cancer-killing toxins without harming the stem cells themselves, and used them to treat mice following brain tumor surgery.


Type 2 diabetes risk may be influenced by blood type

from MNThaem - 22 Dec 14

An individual's blood type may affect their risk of developing type 2 diabetes; people with blood group O are at lowest risk of the condition, according to a new study.


Moderate alcohol benefits: only for 15% of population

from MNTcvs - 15 Nov 14

A new study confirms that moderate alcohol consumption can protect against coronary heart disease, but only for the 15% of the population that have a particular genotype.


Low-carb, high-fat diets may reduce epilepsy seizures

from MNTcvs - 30 Oct 14

Scientists find that diets high in fat and low in carbohydrates, such as the ketogenic diet or modified Atkins diet, may reduce seizures in adults with refractory epilepsy.


Frail 'need joint NHS and care fund'

from BBC - 09 Jul 14

NHS and council-run social-care budgets should be combined for some of the most vulnerable people, the NHS England chief executive says.


The top mistakes patients make when selecting an IVF clinic

from Dr and Patient - 26 May 14

Infertile patients know that IVF is a complex and expensive treatment . It requires a lot of experience and expertise in order to maximize the success rates. They also know that different IVF clinics have different success rates , and that there is a big difference between the pregnancy rates of a good clinics versus a bad clinic. This is why they spend so much time trying to find the best IVF clinic with the highest success rate.However, inspite of this, many patients do a poor job in selecting


Health promotion efforts in schools really do improve health

from MNTpaeds - 28 Apr 14

Can school efforts really persuade kids not to smoke, spur teens to exercise and get little ones to eat more fruits and veggies?


Making drinking illegal before 21 saves lives

from MNTpaeds - 25 Feb 14

Although some advocates want to lower the legal drinking age from 21, research continues to show that the law saves lives. That's the finding of a new review published in a special supplemental issue to the Journal of Studies on Alcohol and Drugs.Researchers found that studies done since 2006 - when a new debate over age-21 laws flared up - have continued to demonstrate that the mandates work.


Schizophrenia linked to increased risk of autoimmune diseases

from MNTschiz - 25 Feb 14

People suffering from schizophrenia are at greater risk of developing autoimmune diseases such as psoriasis and multiple sclerosis. This is the conclusion of new research from Aarhus University. It appears that infections play a determining role.


Dental calculus offers a window into the past, may unlock a 'microbial Pompeii'

from MNTdentistry - 25 Feb 14

An international team of researchers have discovered a 'microbial Pompeii' preserved on the teeth of skeletons around 1,000 years old. The key to the discovery is the dental calculus (plaque) which preserves bacteria and microscopic particles of food on the surfaces of teeth, effectively creating a mineral tomb for microbiomes.


Pharmacological management of tetanus: an evidence-based review

from Critical Care Forum - 26 Mar 14

Tetanus is becoming rarer in both industrialized and developing nations due to an effective vaccination program. In 2010, the World Health Organization estimated there was a 93% reduction in newborns dying from tetanus worldwide, compared to the situation in the late 1980s. Due to its rarity, many diagnostic delays occur as physicians may not consider the diagnosis until the manifestations become overt. Without timely diagnosis and proper treatment, severe tetanus is fatal (mortality is also inf


High carb diet may increase your risk of dementia

from MNTdementia - 25 Feb 14

Even small increases in blood sugar caused by a diet high in carbohydrates can be detrimental to brain health. Recent reports in medical literature link carbohydrate calorie-rich diets to a greater risk for brain shrinkage, dementia and Alzheimer's disease, impaired cognition, and other disorders.


Practice may not make perfect after all, study suggests

from MNTpsych - 11 Jan 14

We are all familiar with the saying "practice makes perfect." But new research from psychologists at the University of Sheffield in the UK suggests that when it comes to learning new skills, the way one practices is more important than the frequency of practice.


Greater experience causes older brains to slow down, study shows

from MNTdementia - 26 Jan 14

We are all familiar with the saying "older but wiser." And new research may prove this to be true. A new study published in the journal Topics in Cognitive Science suggests that as we age, our brain functions slow down as a result of greater experience, not because of cognitive decline.According to the research team, led by Dr.


A person's 'will to persevere' may be evoked by electrical brain stimulation

from MNTpsych - 10 Dec 13

What gives some people the ability to persevere through difficult situations that others may find insurmountable? The answer is no doubt a complicated one that may be beyond our full understanding, but new research published online in the Cell Press journal Neuron provides some intriguing insights.


Our brains can correct us if we make mistakes interpreting the emotions of others

from MNTneuro - 14 Oct 13

When we are sad the world seemingly cries with us. On the contrary, when we are happy everything shines and all around people's faces seem to rejoyce with us. These projection mechanisms of one's emotions onto others are well known to scientists, who believe they are at the core of the ability to interpret and relate to others...


Improving student health at elementary and middle schools

from MNTpaeds - 12 Aug 13

Despite widespread cuts to physical education classes and recess, an Indiana University study has shown that schools can play an important role in helping their students live healthier lives. Schools that implemented coordinated school health programs saw increases in students' physical activity...


Biomarker assessment in suspected acute coronary syndrome could be practice-changing: BIC-8 results

from MNTcvs - 05 Sep 13

An emergency department strategy that uses two biomarkers to triage patients with suspected acute coronary syndrome (ACS) can increase the rate of early, safe hospital discharge, according to results of the Biomarkers in Cardiology 8 (BIC-8) trial...


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