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High Incidence of Gastrointestinal Tract Disorders and Autoimmunity in Primary Cutaneous Marginal Zone B-Cell Lymphomas

from ArchDerm - 01 Apr 14

ImportanceTo our knowledge, this is the first comprehensive study addressing comorbidities associated with primary cutaneous marginal zone B-cell lymphomas (PCMZLs).ObjectiveTo determine if patients with PCMZL were at risk for other medical conditions.Design, Setting, and ParticipantsCase-control study at a cutaneous lymphoma clinic and a dermatopathologic consultation service at a single academic institution using an extensive questionnaire of illnesses, symptoms, and environmental exposures fo



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The Reliability of Teledermatology to Triage Inpatient Dermatology Consultations

from ArchDerm - 01 Apr 14

ImportanceMany hospitals do not have inpatient dermatologic consultative services, and most have reduced availability of services during off-hours. Dermatologists based in outpatient settings can find it challenging to determine the urgency with which they need to evaluate inpatients when consultations are requested. Teledermatology may provide a valuable mechanism for dermatologists to triage inpatient consultations and increase efficiency, thereby expanding access to specialized care for hospi



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Long-term Plasmapheresis in Conjunction With Thalidomide and Dexamethasone for the Treatment of Cutaneous Ulcers and Neovascular Glaucoma in Recalcitrant Type I Cryoglobulinemia

from ArchDerm - 01 Apr 14

ImportanceCryoglobulins are cold-precipitating immunoglobulins that occur secondary to lymphoproliferative disorders, chronic viral infections, and autoimmune disorders. The treatment of cryoglobulinemia should target the underlying disorder; however, such an approach may be difficult, and therapeutic options remain limited for type I cryoglobulinemia.ObservationsWe report a case of recalcitrant type I cryoglobulinemia treated successfully with long-term plasmapheresis in conjunction with thalid



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Dermoscopic Findings in Cutaneous Metastases

from ArchDerm - 01 Apr 14

ImportanceCutaneous metastases rarely develop in patients with cancer but have important implications for prognosis and treatment. While dermoscopy is useful for many skin lesions, few data exist regarding dermoscopic findings in cutaneous metastases.ObservationsWe reviewed high-quality dermoscopic images of 20 outpatients with biopsy-proven cutaneous metastases and known diagnosis of underlying visceral malignancy and correlated these findings with clinical and histologic data. Most lesions wer



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Risk Prediction Models for Incident Primary Cutaneous Melanoma A Systematic Review

from ArchDerm - 01 Apr 14

ImportanceCurrently, there is no comprehensive assessment of melanoma risk prediction models.ObjectiveTo systematically review published studies reporting multivariable risk prediction models for incident primary cutaneous melanoma for adults.Evidence ReviewEMBASE, MEDLINE, PREMEDLINE, and Cochrane databases were searched to April 30, 2013. Eligible studies were hand searched and citation tracked. Two independent reviewers extracted information.FindingsNineteen studies reporting 28 melanoma pred







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Development of a Tongue-Piercing Method for Use With Assistive Technology

from ArchDerm - 01 Apr 14

Piercing the tongue for wearing jewelry is not infrequent among young adults. The procedure is not usually performed by medical personnel. A new assistive technology for people with tetraplegia, the Tongue Drive System (TDS), utilizes voluntary tongue movements for control. The operator uses a magnet attached to the tongue together with an externally mounted sensor array that detects changes in the magnetic field to drive powered wheelchairs and access computers. We hypothesized that a magnet-co



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Expression of Phosphodiesterase-5 in Lymphatic Malformation Tissue

from ArchDerm - 01 Apr 14

Lymphatic malformations (LMs) are uncommon and sometimes debilitating congenital vascular anomalies that presumably arise because of developmental dysplasia of the lymphatic network in utero. They comprise primitive lymphatic sacs surrounded by a thickened layer of connective tissue and interspersed muscle fibers. Current treatments for LM are palliative and only partially successful and include compression, surgical resection, laser ablation, and sclerotherapy. A recent report by Swetman and co



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Improving Accessibility to Inpatient Dermatology Through Teledermatology

from ArchDerm - 01 Apr 14

Inpatient dermatology as a subspecialty has matured during the past decade. However, even when admitted for a dermatologic-specific diagnosis, only 51% of patients receive a dermatologic consultation. Several factors contribute to the lack of accessible dermatologists, including the dermatologic workforce shortage, the location of most dermatologists in outpatient settings away from hospitals, low remuneration for time spent in the hospital, unease in caring for the diseases seen in hospitalized



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Multibranched Acquired Periungual Fibrokeratoma

from ArchDerm - 01 Apr 14

We have encountered a case of multibranched acquired periungual fibrokeratoma (APF).



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Treatment of Giant Cellulitis-like Sweet Syndrome With Dapsone

from ArchDerm - 01 Apr 14

Sweet syndrome is an inflammatory condition characterized by the abrupt development of erythematous plaques accompanied by fever and neutrophilia. Different clinical presentations of this disorder have been described in the literature. We read with interest a recent report in JAMA Dermatology describing a new clinical variant of Sweet syndrome, namely, giant cellulitis-like Sweet syndrome. Clinically these patients develop large, red erythematous plaques that recur and often are misdiagnosed as



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Toward a Practical Renaming of Bullous Pemphigoid and All Its Variants Cutaneous Pemphigoid

from ArchDerm - 01 Apr 14

To the Editor We read with interest the study of Bakker et al emphasizing that pruritus is an important symptom of bullous pemphigoid (BP). Nevertheless, a number of points warrant respectful comment.



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Toward a Practical Renaming of Bullous Pemphigoid and All Its Variants—Reply

from ArchDerm - 01 Apr 14

In Reply We are pleased to see that our article has evoked a relevant discussion on the naming of bullous pemphigoid (BP) and its nonbullous variants.



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Error in Byline

from ArchDerm - 01 Apr 14

In the Observation entitled “Eruptive Cherry Hemangiomatosis Associated With Multicentric Castleman Disease: A Case Report and Diagnostic Clue,” published in the February 2013 issue of JAMADermatology (2013;149[2]:204-208. doi:10.1001/jamadermatol.2013.1552), the first author’s name should have been given as David C. Fajgenbaum. This article was corrected online.



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The Rob

from ArchDerm - 01 Apr 14

The Journal of Cutaneous DiseasesApril 1914MEDICAL RECORD(June 7, 1913, lxxxiii, No. 93)Abstracted by Louis Chargin, M.D.THE ROB. J. B. Stein, p. 1020This is an interesting exposition of the remedies, the so called “Robs,” secret specifics (antisyphilitic) of much vogue in the 18th and 19th centuries in France and other countries. It was first introduced in 1761 and is supposedly still on the market. The paper is of historical interest.J Cutan Dis. 1914;32(4):335.



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Strange Bedfellows

from ArchDerm - 01 Apr 14

Brünauer-Fuhs-Siemens syndrome, or keratosis palmoplantaris striata type 1 (OMIM 148700), is caused by mutations in desmoglein 1. Between 1924 and 1929, 3 German-speaking dermatologists described this disease. While their names are always grouped together in this eponym, it is difficult to imagine a more unlikely trio.



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The Forehead Scar as a Literary Device

from ArchDerm - 01 Apr 14

Dermatologists and patients often view scars as imperfections. In literature, however, scars can help define a nuanced character, often revealing more than other aspects of a character’s appearance. Does the scar connote bravery, some triumph in battle? Or, could it mean something more sinister, a memento of treachery perhaps?



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From Elizabeth Bennet to Barbie Sun Tanning Through the Ages

from ArchDerm - 01 Apr 14

Never mind the little black dress; Coco Chanel’s most lasting contribution to the world of style—and, unfortunately, to dermatology—may well be the suntan. For centuries, in a fashion statement freighted with racial undertones, women around the world coveted a fair complexion. Ancient Egyptians lightened their skin with myrrh and frankincense. Eighth-century Japanese women risked death, using lead and mercury as whiteners. Intent on showing they had never needed to labor under the sun, 18th-cent



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The Men or Women Behind Nevi: Alfred Guido Miescher

from ArchDerm - 01 Apr 14

The man behind Miescher nevus is Alfred Guido Miescher. He was born on November 4, 1887, in Naples, Italy. His mother was Marietta Berner, and his father, Max Eduard Miescher, was a businessman. He was the nephew of Johannes Friedrich Miescher (1844-1895), professor of pathophysiology at the University of Basel, Switzerland, and discoverer of nucleic acids. After the father’s death, he followed his mother to Basel, her hometown, where Guido completed his school.



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JAMA Dermatology

from ArchDerm - 01 Apr 14

Mission Statement: JAMA Dermatology publishes information concerning the skin, its diseases, and their treatment. Its mission is to explicate the structure and function of the skin and its diseases and the art of using this information to deliver optimal medical and surgical care to the patient. We attempt to enhance the understanding of cutaneous pathophysiology and improve the clinician's ability to diagnose and treat skin disorders. This journal has a particular interest in publishing clinica



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New study shows flu vaccine reduced children's risk of intensive care unit flu admission by three-fourths

from MNTpaeds - 31 Mar 14

Getting a flu vaccine reduces a child's risk of flu-related intensive care hospitalization by 74 percent, according to a CDC study published in the Journal of Infectious Diseases. The study is the first to estimate vaccine effectiveness (VE) against flu admissions to pediatric intensive care units (PICU).



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Public resistance to soda tax, size restrictions

from MNTpaeds - 31 Mar 14

Those hoping to dilute Americans' taste for soda, energy drinks, sweetened tea, and other sugary beverages should take their quest to school lunchrooms rather than legislative chambers, according to a recent study by media and health policy experts.Soda taxes and beverage portion size restrictions were unpalatable to the 1,319 U.S.


 

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