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Influence of the American Society of Hematology Guidelines on the Management of Newly Diagnosed Childhood Immune Thrombocytopenia

from ArchPedi - 06 Oct 14

ImportanceIn 2011, the American Society of Hematology (ASH) published updated guidelines for the management of childhood immune thrombocytopenia (ITP) recommending management with observation alone when there are mild or no bleeding symptoms, regardless of platelet count. Little is known about practice patterns of newly diagnosed ITP in the United States.ObjectiveTo understand the impact of management recommendations on practice patterns.Design, Setting, and ParticipantsRetrospective medical rec



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Novel gene/cell therapy approach developed for lung disease

from MNTpaeds - 04 Oct 14

Researchers developed a new type of cell transplantation to treat mice mimicking a rare lung disease that one day could be used to treat this and other human lung diseases caused by dysfunctional...



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Grandparents' support linked to parents' willingness to have additional children and child well-being

from MNTpaeds - 03 Oct 14

Grandparents can significantly influence parents' decisions to have additional children and the well-being of grandchildren, according to a recent study completed at the University of Eastern Finland.



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Free birth control reduces teen pregnancies and abortions

from MNTpaeds - 03 Oct 14

Teens who received free contraception and were educated about the pros and cons of various birth control methods were dramatically less likely to get pregnant, give birth or get an abortion compared...



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HIV rebounds in second baby thought to have been cured with early treatment

from MNTpaeds - 03 Oct 14

A new report published in The Lancet reveals that HIV has returned in a baby believed to have been cured of the virus with early antiretroviral therapy.



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Do expectant moms receive adequate information on Down syndrome?

from MNTpaeds - 02 Oct 14

Down Syndrome Awareness Month: we investigate the - sometimes controversial - arguments surrounding pregnancy and the condition. Tomorrow, we look at advances in Down research.



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Twitches during REM sleep activate the brain in a unique way, providing further evidence that sleep twitches teach newborns about their bodies

from MNTpaeds - 02 Oct 14

A University of Iowa study has found twitches made during sleep activate the brains of mammals differently than movements made while awake.



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Chef-made meals can increase school meal participation and vegetable intake among students

from MNTpaeds - 02 Oct 14

Gourmet pizza in school? According to a new Food and Brand Lab pilot study, published in Appetite, chef-made meals can increase participation in the National School Lunch Program (NSLP) by 9% and...



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Before they're even old enough to speak: researcher improves babies' language skills

from MNTpaeds - 02 Oct 14

In the first months of life, when babies begin to distinguish sounds that make up language from all the other sounds in the world, they can be trained to more effectively recognize which sounds...





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Involvement of Plasmacytoid Dendritic Cells in the Immunological Response Against Orf Infection

from ArchDerm - 01 Oct 14

Plasmacytoid dendritic cells (PDCs) are specialized dendritic cells with a significant role in antiviral resistance. Plasmacytoid dendritic cells have never been studied in orf infection.



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The Impact Dermatologists Can Have on Misdiagnosis of Cellulitis and Overuse of Antibiotics Closing the Gap

from ArchDerm - 01 Oct 14

We have all experienced the patient with red legs, referred for refractory “cellulitis” not responding to systemic antibiotics. Primary care, urgent care, hospitalist, and emergency department physicians are on the front line seeing these patients; however, they often lack the training that allows them to recognize cellulitis mimickers. This constitutes a practice gap. Patients are overdiagnosed as having cellulitis, leading to inappropriate use of antibiotics and unnecessary hospitalizations dr



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Granuloma Inframammary Adultorum

from ArchDerm - 01 Oct 14

Granuloma inframammary adultorum represents a variant of erosive papulonodular dermatosis (EPND) with predominant clinical components of papules and nodules. We describe herein a patient who presented with worsening skin lesions.



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A Unilateral Orbital Mass

from ArchDerm - 01 Oct 14

Orbital fat herniation frequently presents as a prominent unilateral mass near the lateral canthus of the eye, where it poses a fundamental question: benign or malignant? As dermatologists, we will encounter this seldom-described benign mass. The differential diagnosis, pathophysiology, and treatment options are discussed in the context of a patient case.



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Zinc Deficiency and Canities An Unusual Manifestation

from ArchDerm - 01 Oct 14

Zinc is an essential trace element in health and disease. It chiefly functions as a cofactor to various metalloproteins and enzymes and is involved in transcription and gene expression. In contrast to Western countries, acquired zinc deficiency is common in South Asian countries principally in infants and young children due to poor diet and malnutrition. Herein we describe an infant with canities due to acquired zinc deficiency, which to our knowledge has not been described previously, and also



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Exogenous Pigmentation Mimicking Acral Melanoma A Case of Talon d’Oyer

from ArchDerm - 01 Oct 14

We report the case of a patient with a history of malignant melanoma who presented to our clinic with a “new brown spot” on her heel.



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Cutaneous Embolization of Doxorubicin Drug-Eluting Beads

from ArchDerm - 01 Oct 14

Transarterial chemoembolization (TACE) with drug-eluting microspheres (DEMs) is emerging as the therapy of choice by many interventional oncologists and radiologists for unresectable liver tumors. Improvements in drug delivery systems have been made by modification of the embolic agents and the introduction of microcatheters, allowing for precise drug delivery to tumors. Currently, DEMs are being used as the drug delivery system for TACE. We report herein a case of cutaneous embolization of doxo




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Error in Byline

from ArchDerm - 01 Oct 14

In the article titled “Association of Pain and Itch With Depth of Invasion and Inflammatory Cell Constitution in Skin Cancer: Results of a Large Clinicopathologic Study,” published online July 23, 2014, in JAMA Dermatology (doi:10.1001/jamadermatol.2014.895), the fifth author’s name was incorrect and should have been given in the byline as Hong Liang Tey, MD. Consequently, the third institution and affiliations in the Author Affiliations section should have appeared as “Department of Dermatolog



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Dermatitis Dysmenorrhœica Symmetrica

from ArchDerm - 01 Oct 14

The Journal of Cutaneous DiseasesOctober 1914FURTHER CONTRIBUTIONS ON DERMATOSIS DYSMENORRHŒICA SYMMETRICA (MATZENAUER-POLLAND). R. Polland, p. 260.Polland takes up the cudgels in defense of the recently described clinical entity of dermatosis dysmenorrhœica symmetrica, and stoutly repudiates the hostile suggestion that the condition is indigenous only to the vicinity of the Graz clinic. A number of very interesting new cases are presented, including a note on the one described by Friedberg in B



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Famous Lines in History Blaschko Lines

from ArchDerm - 01 Oct 14

The lines of Blaschko describe a linear pattern of distribution of various congenital, nevoid, and acquired skin disorders with their suspected embryological origins not yet well understood. These lines were painstakingly and thoroughly documented first by German dermatologist Alfred Blaschko. Blaschko was the son of a physician and was born in 1858 in Freienwalde and died in 1922 in Berlin. He was a private practitioner in Berlin, where his dermatologic interests ranged from dermatitis herpetif



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Famous Lines in History Langer Lines

from ArchDerm - 01 Oct 14

The orientation of surgical incisions over the skin is widely considered to affect scarring and the final cosmetic outcome for patients. When most surgeons visualize lines on the skin surface to guide such incisions, it is Langer lines (also known as skin cleavage or tension lines) that most readily come to mind. Karl Langer (1819-1887), the man behind the famous lines, was born in Vienna, Austria, where he spent most of his life and later became professor of anatomy at Joseph’s Academy. In 1861



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The Subcutaneous Splint A Helpful Analogy to Explain Postoperative Wound Eversion

from ArchDerm - 01 Oct 14

Dermatologists are responsible for a large proportion of surgical reconstructive procedures in the United States. As the number of surgical encounters increases with our aging population, we as physicians continue to encounter new patients for whom the immediate postoperative appearance of a surgical site represents a novel experience.



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JAMA Dermatology

from ArchDerm - 01 Oct 14

Mission Statement: JAMA Dermatology publishes information concerning the skin, its diseases, and their treatment. Its mission is to explicate the structure and function of the skin and its diseases and the art of using this information to deliver optimal medical and surgical care to the patient. We attempt to enhance the understanding of cutaneous pathophysiology and improve the clinician's ability to diagnose and treat skin disorders. This journal has a particular interest in publishing clinica


 

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