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Cystic Fibrosis-Associated Intestinal Obstruction Ameliorated By Gene Replacement In Pigs

from MNTcf - 10 May 13

Cystic fibrosis (CF) is caused by mutations in CFTR and is characterized by dysfunction of the lungs, liver, pancreas, and intestines. Approximately 15% of babies with CF are born with an obstruction of the small intestine known as meconium ileus, frequently the first sign of CF. Unlike in humans, meconium ileus occurs in 100% of newborn CF pigs...

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Is There A Healthy Fast Food Option?

from MNTpaeds - 10 May 13

Subway may promote itself as the "healthy" fast food restaurant, but it might not be a much healthier alternative than McDonald's for adolescents, according to new UCLA research. In a study published in the Journal of Adolescent Health, the researchers found that adolescents who purchased Subway meals consumed nearly as many calories as they did at McDonald's...

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For Children With Common Conditions, Hospital Readmissions Affected By Nurse Staffing Ratios

from MNTpaeds - 10 May 13

A new study shows that pediatric nurse staffing ratios are significantly associated with hospital readmission for children with common medical and surgical conditions. The study, led by a nurse scientist at Cincinnati Children's Hospital Medical Center, is believed to be the first to examine the extent to which hospital nurse staffing levels are related to pediatric readmissions...

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Serendipitous Scientific Discovery Holds Potential In Destroying Drug-Resistant Bacteria

from MNTcf - 10 May 13

Through the serendipity of science, researchers at the University of Pittsburgh have discovered a potential treatment for deadly, drug-resistant bacterial infections that uses the same approach that HIV uses to infect cells. The National Institutes of Health-supported discovery will be described in the June issue of the journal Antimicrobial Agents and Chemotherapy...

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Early Infant Growth Rate Linked To Composition Of Gut Microbiota

from MNTpaeds - 09 May 13

The composition of gut microbiota in a new-born baby's gut has been linked to the rate of early infant growth, reports research published this week in PLOS Computational Biology. The findings support the assertion that the early development of "microbiota" - the body's microbial ecosystem - in an infant can influence growth and thereby the likelihood of obesity...

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Wrigley Takes Caffeinated Gum Off The Market Over FDA Concerns

from MNTpaeds - 09 May 13

Wrigley will remove caffeinated gum from the market after an investigation announcement by the Food and Drug Administration (FDA), the company said yesterday...

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Parents Help Detect Sleep Problems In Children With Down Syndrome

from MNTpaeds - 09 May 13

A recent study has found that parents play an important part in screening for sleep problems in children with Down syndrome. These children often suffer from obstructive sleep apnoea, a condition which affects their breathing during sleep...

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Protecting Preterm Infants From Disturbing Light

from MNTpaeds - 09 May 13

Preterm infants appear to mature better if they are shielded from most wavelengths of visible light, from violet to orange. But it has been a challenge to develop a controllable light filter for preterm incubators that can switch between blocking out all light - for sleeping - and all but red light to allow medical staff and parents to check up on the kids when they're awake...

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Reducing Dangers Of Lead Poisoning

from MNTpaeds - 09 May 13

A new study appearing this week in the Journal of Health Politics, Policy, and Law catalogues community-based efforts to develop strategies and policies that - by targeting high risk housing - may hold the key to reducing lead hazards in children's homes. "Lead poisoning has long been characterized as a health problem with a housing solution," said Katrina Korfmacher, Ph.D...

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Study Examines Effect Of Different Oxygen Saturation Levels On Death Or Disability In Extremely Preterm Infants

from MNTpaeds - 08 May 13

In a randomized trial performed to help resolve the uncertainty about the optimal oxygen saturation therapy in extremely preterm infants, researchers found that targeting saturations of 85 percent to 89 percent compared with 91 percent to 95 percent had no significant effect on the rate of death or disability at 18 months, according to a study published by JAMA...

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SUSTIVA® (Efavirenz) Receives US FDA SNDA Approval For Use In HIV-1 Infected Pediatric Patients

from MNTpaeds - 08 May 13

Approval offers a once-daily option as part of a regimen for HIV-1 infected infants as young as three months and weighing at least 3.5 kg. "Capsule sprinkle" administration allows dosing in patients who cannot swallow capsules or tablets. Bristol-Myers Squibb Company have announced that the U.S...

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Progerin's 'Discrimination' May Contribute To Fatal Disease That Resembles Premature Aging

from MNTpaeds - 08 May 13

A mutant protein responsible for Hutchinson-Gilford Progeria syndrome (HGPS) bars large proteins from entering the nucleus, according to a study in The Journal of Cell Biology. The culprit in HGPS, a fatal disease that resembles premature aging, is a protein variant called Progerin. This defective protein impairs cells in many ways, including reducing nuclear levels of the RanGTPase...

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Hydrocarbons In Cleaners And Fuels Pose Major Risk To Children

from MNTpaeds - 08 May 13

Hydrocarbons, a chemical compound commonly found in household items from cleaning products to gasoline, are among the top 10 causes of pediatric poisoning deaths in the United States...

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Pumpless Paracorporeal Assist Device Helps Infants With Severe Respiratory Failure Survive Until Lung Transplantation

from MNTpaeds - 08 May 13

Adults with end-stage respiratory failure and pulmonary hypertension requiring ECMO (extracorporeal membrane oxygenation) have been "bridged" toward lung transplantation with novel lung assist devices such as the Novalung. This and related devices work based on pumpless application of oxygenators. A presentation by David M...

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Higher Blood Lead Levels - Resulting In Lower IQ - Discovered In Children Living Near Toxic Waste Sites

from MNTpaeds - 08 May 13

Children living near toxic waste sites in lower and middle income countries such as India, Philippines and Indonesia may experience higher blood lead levels, resulting in a loss of IQ points and a higher incidence of mental retardation, according to a study presented by Kevin Chatham-Stephens, MD, Pediatric Environmental Health Fellow at the Icahn School of Medicine at Mount S...

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Teen Smokers May Be At Greater Risk Of Marijuana Addiction

from MNTpaeds - 07 May 13

Teen smokers who rationalize their use of cigarettes by saying, "At least, I'm not doing drugs," may not always be able to use that line. New research presented at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC, supports the theory that cigarettes are a gateway drug to marijuana...

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800 IU Of Vitamin D3 Per Day May Be Necessary For Preterm Infants

from MNTpaeds - 07 May 13

Preterm infants may need to be given 800 international units (IU) of vitamin D a day to ensure they develop strong bones, according to a study presented at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. Preemies are known to be at risk for vitamin D insufficiency...

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Exposure To Flame Retardants During Pregnancy May Damage Developing Fetus

from MNTpaeds - 07 May 13

Chemicals called polybrominated diphenyl ethers (PBDEs) have been used for decades to reduce fires in everyday products such as baby strollers, carpeting and electronics. A new study presented on Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting shows that prenatal exposure to the flame retardants is associated with lower intelligence and hyperactivity in early childhood...

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High School Females Who Run, Play Sports Are At Lower Risk Of Fighting, Being In A Gang

from MNTpaeds - 07 May 13

Regular exercise is touted as an antidote for many ills, including stress, depression and obesity. Physical activity also may help decrease violent behavior among adolescent girls, according to new research presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC...

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Survey Of High School Football Players Shows Many Would Not Report Concussion Symptoms To A Coach

from MNTpaeds - 07 May 13

Many high school football players say it's OK to play with a concussion even though they know they are at risk of serious injury, according to a study presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC...

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Fewer Deaths Among Youths After A Bicycle-Motor Vehicle Crash In States With Mandatory Helmet Laws

from MNTpaeds - 07 May 13

Bicycle helmets save lives, and their use should be required by law. That's the conclusion of a study presented Monday, May 6, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC. "This study highlights the importance of regulations in the promotion of safe exercise," said lead author William P...

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Child Passengers Often In Cars With Distracted Drivers; Many Youngsters Also Not In The Right Size Safety Seat

from MNTpaeds - 07 May 13

Many parents are putting their precious cargo at risk while driving, according to survey results that were presented May 5 and 6 at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC...

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The Health Of U.S. Children Threatened By Poverty

from MNTpaeds - 07 May 13

Pediatricians, economists, social scientists and policy experts met to address one of the greatest threats to child health - poverty. The group took part in a plenary session titled, "A National Agenda to End Childhood Poverty," at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC...

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Children Who Live In 'Walkable' Neighborhoods Are Less Likely To Be Overweight

from MNTpaeds - 07 May 13

As parents, physicians and policymakers look for ways to curb childhood obesity, they may need to look no further than a child's own backyard. A new study presented at the Pediatric Academic Societies (PAS) annual meeting shows that preschool children are less likely to be obese if they live in a neighborhood that is safe and within walking distance of parks and retail services...

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43 Percent Of Youths Admit To Texting While Driving; Prevalence Higher Among Males, Older Teens

from MNTpaeds - 07 May 13

Don't txt n drive: Teens not getting msg Teens can get hundreds of text messages a day, but one message they aren't getting is that they shouldn't text and drive...

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