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Mechanism found that regulates lung function in disease Birt-Hogg-Dube syndrome

from MNTderm - 14 Apr 14

Researchers at Penn Medicine have discovered that the tumor suppressor gene folliculin (FLCN) is essential to normal lung function in patients with the rare disease Birt-Hogg-Dube (BHD) syndrome, a...



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Applying lessons learned from fetal skin to reduce scarring in adult wounds

from MNTderm - 14 Apr 14

In early fetal development, skin wounds undergo regeneration and healing without scar formation.



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Drugs that reverse fibrosis in scleroderma step closer

from MNTderm - 07 Apr 14

Researchers say they have discovered a promising target for new drugs that might be able to reverse the fibrosis process in systemic sclerosis or scleroderma - a rare disease that cuts short the lives of many patients and for which there is no cure or effective treatment.



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Minorities would benefit from increased awareness about skin cancer

from MNTderm - 26 Mar 14

More awareness about skin cancer is needed for minorities because they believe they are at low risk of developing it, says Henry Ford Hospital dermatologist Diane Jackson-Richards, M.D.Research has shown that minorities are diagnosed at a more advanced stage of skin cancer and have lower chances of survival than Caucasians.



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Non-invasive gene expression profile test shown to identify sentinel lymph node negative melanoma patients at high risk of metastasis

from MNTderm - 25 Mar 14

Castle Biosciences Inc. has announced study results showing its gene expression profile (GEP) test (DecisionDx-Melanoma) can identify primary cutaneous (skin) melanoma tumors that are likely to metastasize in patients who had a negative sentinel lymph node biopsy.



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Abandoned antibiotic makes a comeback

from MNTderm - 21 Mar 14

Scarlet fever and infections of the skin and throat are often caused by a bacterium called Streptococcus pyogenes. In less-developed countries, inexpensive and well-tolerated antibiotics for therapy are often not available. Scientists of the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany, have discovered that trimethoprim may provide an option.



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Promising new research on reducing pressure ulcers

from MNTderm - 17 Mar 14

According to a new study published in The American Journal of Critical Care, "Continuous Bedside Pressure Mapping and Rates of Hospital-Associated Pressure Ulcers in a Medical Intensive Care Unit," continuous bedside pressure mapping (CBPM) provided caregivers with a useful monitor to assess the effectiveness of repositioning patients off of pressure areas, a crucial component of providing better...



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Skin abscesses caused by MRSA: new treatment guidelines issued

from MNTderm - 14 Mar 14

It has been more than 10 years since the clinical battle began with community-acquired methicillin-resistant Staphylococcus aureus (MRSA), and doctors are still grappling with how to diagnose, treat and prevent this virulent form of staph infection, which is immune to many antibiotics.



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In new approach to tissue engineering scientists 'herd' cells

from MNTderm - 13 Mar 14

Sometimes it only takes a quick jolt of electricity to get a swarm of cells moving in the right direction.



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Injections of fillers for cosmetic treatment can open the door to bacteria

from MNTderm - 13 Mar 14

Many people have 'fillers' injected into their facial tissue to give them 'bee-stung lips' or to smooth out their wrinkles. Unfortunately, a lot of cosmetic treatment customers experience unpleasant side effects in the form of tender subcutaneous lumps that are difficult to treat and which - in isolated cases - have led to lesions that simply will not heal.



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Bacterial secretion system unraveled to understand spread of antibiotic resistance

from MNTderm - 11 Mar 14

The system that allows the sharing of genetic material between bacteria - and therefore the spread of antibiotic resistance - has been uncovered by a team of scientists at Birkbeck, University of London and UCL.The study, published in Nature, reveals the mechanism of bacterial type IV secretion, which bacteria use to move substances across their cell wall.



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Young nonmelanoma skin cancer survivors more likely to get other cancers later

from MNTderm - 07 Mar 14

People who had nonmelanoma skin cancer (NMSC) were at increased risk for subsequently developing melanoma and 29 other cancer types, and this association was much higher for those under 25 years of age, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.NMSC is the most common type of skin cancer.



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Researchers test range of electrical frequencies that help heal chronic wounds

from MNTderm - 06 Mar 14

Naturally occurring electricity in our cells is key to how our bodies function, and that includes the healing of wounds.Hard-to-heal wounds, like diabetic ulcers, fester because of insufficient blood supply at the wound site.



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New indications for prevention of sun damage associated with aging and skin cancer

from MNTderm - 05 Mar 14

Journal of Drugs in Dermatology (JDD) has released a clinical study highlighting the efficacy of Triple Protection Factor Broad Spectrum Sunscreen, TPF 50, to prevent skin sun damage and Non-Melanoma Skin Cancer (NMSC). In this head-to-head comparison study, investigators Enzo Emanuele MD, PhD, James M.



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New discovery solves problem of anti-inflammatory substance

from MNTderm - 03 Mar 14

There have been great expectations regarding the production of a drug to block the enzyme LTA4 hydrolase, which plays a key role in the body's inflammatory response. However, in clinical trials, such molecules have proven to be only moderately effective.



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New strategies for the treatment of psoriasis

from MNTderm - 03 Mar 14

Drugs against newly identified targets might be developed with potentially fewer side effectsAlmost ten years ago, the group led by Erwin Wagner, currently at the Spanish National Cancer Research Centre (CNIO), developed genetically modified mice showing symptoms very reminiscent to psoriasis.



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Mirvaso® (brimonidine) the first and only treatment targeting the facial redness of rosacea approved by the European Commission

from MNTderm - 27 Feb 14

Galderma, a leading global pharmaceutical company exclusively focused on dermatology, today announced that the European Commission has granted Marketing Authorisation in Europe for Mirvaso® (brimonidine) 3 mg/g gel.Mirvaso® is an alpha-2 adrenergic receptor agonist that acts rapidly and can last for up to 12 hours.



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Sunburns strike twice

from MNTderm - 27 Feb 14

Melanoma is particularly dangerous because it can form metastases in vital organs such as the lungs, liver or brain. UV radiation is considered to be the most significant triggering factor.



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Diabetic foot ulcers healed, amputation prevented by tissue repair drug

from MNTderm - 27 Feb 14

Patients were twice as likely to have a diabetic foot ulcer heal within eight weeks when they were treated with a tissue repair drug versus a placebo, according to new research accepted for publication in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).Foot ulcers are a common complication from diabetes than can lead to hospitalization and lower limb amputation.



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Indoor tanning common among high-schoolers, linked to other risky behavior

from MNTderm - 26 Feb 14

A national survey of high school students finds that indoor tanning is a common practice, particularly among female, older and non-Hispanic white students, and is associated with several other risky health-related behaviors, according to a study by Gery P. Guy Jr., Ph.D., M.P.H., of the Centers for Disease Control and Prevention, Atlanta, and colleagues.



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Did a risk of skin cancer drive the evolution of black skin in humans?

from MNTderm - 26 Feb 14

A new analysis suggests that black skin may have evolved in humans as a protective measure against skin cancer.Previously, skin cancer has been disregarded as an influence in the evolution of black skin in humans. This is based on the belief that skin cancer only rarely causes death at ages young enough to affect reproduction.



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Promising skin tumor vaccine offers hope for transplant patients

from MNTderm - 24 Feb 14

Papillomaviruses (linked to cervical cancer when they infect the mucosal tissue in the female reproductive tract) can also infect normal skin, where they cause warts and possibly non-melanoma skin cancer, mostly in immune-suppressed organ transplant patients. An article published in PLOS Pathogens suggests that vaccination might prevent virus-associated benign and malignant skin tumors.



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Better wound healing with bioengineered growth factors

from MNTderm - 24 Feb 14

When we are wounded, our bodies naturally begin a process of repair of the damaged tissue. This process is mediated by biological molecules called growth factors, which are proteins that occur naturally in our cells and guide processes ranging from embryonic development to healing.



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Chemical leak that contaminated drinking water shows gaps in research, policy

from MNTderm - 22 Feb 14

The chemical leak that contaminated drinking water in the Charleston, W.Va., area last month put in sharp relief the shortcomings of the policies and research that apply to thousands of chemicals in use today.



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Parcell Laboratories partners with the University of Pittsburgh medical center to study effective stem cell-based wrinkle treatments

from MNTderm - 21 Feb 14

Parcell Laboratories, developer of novel therapeutics based on its patented adult stem cell platform technology, the ELA® cell, is partnering with the University of Pittsburgh Medical Center (UPMC) to study a new stem cell-based wrinkle reduction treatment.


 

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