• Find us on Facebook
  • Follow BMJ OnExamination on Twitter

Latest News

Like this article?

Click vote now


0

The ForeSeeHome Device and the HOME Study A Milestone in the Self-detection of Neovascular Age-Related Macular Degeneration

from ArchOpht - 01 Oct 14

Since the beginning of neovascular age-related macular degeneration (AMD) therapy, clinicians have been faced with a dilemma—that treatment was most helpful if choroidal neovascularization (CNV) was detected before visual acuity was affected but that identifying patients at this early stage was difficult. Self-detection techniques have been less than satisfactory. For instance, Zaidi et al described only a 30% detection rate on a self-detection protocol that included the use of the Amsler grid.



0

Visual Ability of Patients Seeking Outpatient Low Vision Services in the United States

from ArchOpht - 01 Oct 14

ImportanceMost patients with low vision are elderly and have functional limitations from other health problems that could add to the functional limitations caused by their visual impairments. ObjectiveTo identify factors that contribute to visual ability measures in patients who present for outpatient low vision rehabilitation (LVR) services.Design, Setting, and ParticipantsAs part of a prospective, observational study of new patients seeking outpatient LVR, 779 patients from 28 clinical centers



0

Validity of a Telemedicine System for the Evaluation of Acute-Phase Retinopathy of Prematurity

from ArchOpht - 01 Oct 14

ImportanceThe present strategy to identify infants needing treatment for retinopathy of prematurity (ROP) requires repeated examinations of at-risk infants by physicians. However, less than 10% ultimately require treatment. Retinal imaging by nonphysicians with remote image interpretation by nonphysicians may provide a more efficient strategy.ObjectiveTo evaluate the validity of a telemedicine system to identify infants who have sufficiently severe ROP to require evaluation by an ophthalmologist



0

Novel Recessive Cone-Rod Dystrophy Caused by POC1B Mutation

from ArchOpht - 01 Oct 14

ImportanceA new form of cone-rod dystrophy (CORD) is described and the gene responsible for the disease is identified.ObjectiveTo clinically evaluate 4 patients and 5 control relatives, perform disease gene mapping, and identify the gene defect responsible for CORD.Design, Setting, and ParticipantsProspective observational case series of 13 members of a consanguineous family and 113 unrelated control individuals.InterventionsClinical investigations included eye examination with color fundus and



0

Multicenter Study of Descemet Membrane Endothelial Keratoplasty First Case Series of 18 Surgeons

from ArchOpht - 01 Oct 14

ImportanceSurgeons starting to perform Descemet membrane endothelial keratoplasty (DMEK) should be informed about the learning curve and experience of others.ObjectiveTo document the clinical outcome of standardized “no-touch” DMEK and its complications during the learning curves of experienced surgeons.Design, Setting, and ParticipantsRetrospective multicenter study. A total of 431 eyes from 401 patients with Fuchs endothelial dystrophy (68.2%) and bullous keratopathy (31.8%) underwent DMEK per



0

Regular Examinations for Toxic Maculopathy in Long-term Chloroquine or Hydroxychloroquine Users

from ArchOpht - 01 Oct 14

ImportanceAccording to evidence-based, expert recommendations, long-term users of chloroquine or hydroxychloroquine sulfate should undergo regular visits to eye care providers and diagnostic testing to check for maculopathy.ObjectiveTo determine whether patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) taking chloroquine or hydroxychloroquine are regularly visiting eye care providers and being screened for maculopathy.Design, Setting, and ParticipantsPatients with RA



0

The Relationship of Central Foveal Thickness to Urinary Iodine Concentration in Retinitis Pigmentosa With or Without Cystoid Macular Edema

from ArchOpht - 01 Oct 14

ImportanceCurrent treatments for cystoid macular edema (CME) in retinitis pigmentosa (RP) are not always effective, may lead to adverse effects, and may not restore visual acuity. The present research lays the rationale for evaluating whether an iodine supplement could reduce CME in RP.ObjectiveTo determine whether central foveal thickness (CFT) in the presence of CME is related to dietary iodine intake inferred from urinary iodine concentration (UIC) in nonsmoking adults with RP.Design, Setting



0

Identification of an HMGB3 Frameshift Mutation in a Family With an X-linked Colobomatous Microphthalmia Syndrome Using Whole-Genome and X-Exome Sequencing

from ArchOpht - 01 Oct 14

ImportanceMicrophthalmias are rare disorders whose genetic bases are not fully understood. HMGB3 is a new candidate gene for X-linked forms of this disease.ObjectiveTo identify the causative gene in a pedigree with an X-linked colobomatous microphthalmos phenotype.Design, Setting, and ParticipantsWhole-genome sequencing and chromosome X-exome–targeted sequencing were performed at the High Throughput Sequencing Laboratory of the Genetic Resources Core Facility at the Johns Hopkins University Scho



0

An Implantable Intraocular Pressure Transducer Initial Safety Outcomes

from ArchOpht - 01 Oct 14

ImportanceTo our knowledge, this is a report of the first implantation of a wireless intraocular pressure transducer (WIT) in a human eye.ObjectiveTo report preliminary safety data on the WIT.Design, Setting, and ParticipantIn an institutional setting, a patient with open-angle glaucoma consented to be the recipient of the WIT in one eye in an interventional study design.InterventionsThe WIT was implanted into the ciliary sulcus following extracapsular cataract extraction and “in the bag” intrao



0

The Relationship Between Hepatic Lipase Gene Variant and Advanced Age-Related Macular Degeneration A Meta-analysis

from ArchOpht - 01 Oct 14

ImportanceTo date, no consistency exists across studies that have evaluated the relationship between hepatic lipase gene (LIPC) rs10468017 variant and advanced age-related macular degeneration (AMD).ObjectiveTo summarize all relevant evidence for a relationship between LIPC variant and advanced AMD.Data SourcesThe PubMed and Embase databases were searched for studies potentially eligible in any language published up to September 15, 2013.Study SelectionCase-control studies of 2 or more compariso



0

Hourly Awakening vs Continuous Contact Lens Sensor Measurements of 24-Hour Intraocular Pressure Effect on Sleep Macrostructure and Intraocular Pressure Rhythm

from ArchOpht - 01 Oct 14

ImportanceAll studies of 24-hour intraocular pressure (IOP) rhythm conducted to date have used repeated IOP measurements requiring nocturnal awakenings, potentially disturbing sleep macrostructure.ObjectiveTo evaluate the effects on sleep architecture and IOP rhythm of hourly awakening vs a contact lens sensor (CLS) to continuously monitor IOP without awakening.Design, Setting, and ParticipantsCross-sectional study at a referral center of chronobiology among 12 young healthy volunteers, with a m



0

Association of Vision Loss and Work Status in the United States

from ArchOpht - 01 Oct 14

ImportanceWorking is critical to personal health and well-being. We examine the association of vision measured objectively with work status using a nationally representative sample of working-age Americans.ObservationA total of 19?849 participants from the 1999-2008 National Health and Nutrition Examination Survey completed a vision examination and employment/demographic questionnaires. Employment rates for men with visual impairment, uncorrected refractive error, and normal vision were 58.7%, 6





0

Regression of Choroidal Metastasis From Breast Carcinoma Treated With Gamma Knife Radiosurgery

from ArchOpht - 01 Oct 14

Uveal metastasis is often managed by external beam radiation therapy requiring multiple treatment sessions for the patient. We report the first case, to our knowledge, of regression of choroidal metastasis from breast carcinoma after 1 treatment with Leksell Gamma Knife (GK) stereotactic radiosurgery.



0

Adenocarcinoma of the Retinal Pigment Epithelium Clinicopathologic Correlation With Paradoxical Immunohistochemical Findings

from ArchOpht - 01 Oct 14

True neoplasms can arise from pigment epithelium of the iris, ciliary body, and retina (retinal pigment epithelium [RPE]). We report a large adenocarcinoma of RPE that was a diagnostic challenge based on clinical features, cytopathology, and immunohistochemistry. However, with routine histopathology of the enucleated eye, the diagnosis of RPE adenocarcinoma was established.



0

Late-Onset Retinal Degeneration Caused by C1QTNF5 Mutation Sub–Retinal Pigment Epithelium Deposits and Visual Consequences

from ArchOpht - 01 Oct 14

Two decades ago, a postmortem eye donor study identified a unique autosomal dominant disease and named it late-onset retinal degeneration (L-ORD). The distinguishing feature of L-ORD was a retina-wide thick layer of extracellular deposit between the retinal pigment epithelium (RPE) and Bruch membrane. A founder mutation, p.Ser163Arg, in C1QTNF5 was causative. Recent study of the crystal structure of C1QTNF5 suggested that L-ORD may be caused by reduced adhesion of the RPE.



0

Error in Figure

from ArchOpht - 01 Oct 14

In the article titled “Single vs Multiple Intraocular Pressure Measurements in Glaucoma Surgical Trials,” published online May 15, 2014, and also in the August print issue of JAMA Ophthalmology (2014;132[8]:956-962. doi:10.1001/jamaophthalmol.2014.867), an error occurred in Figure 3 on page 961. In the P Value column, the values should have been shifted down by one row, with no value in the top row (correlating to Time [reference, 12 pm]). This article was corrected online.



0

Incorrect Information in Viewpoint

from ArchOpht - 01 Oct 14

In the Viewpoint entitled “The ForeSeeHome Device and the HOME Study: A Milestone in the Self-detection of Neovascular Age-Related Macular Degeneration” published online July 24, 2014, in JAMA Ophthalmology (doi:10.1001/jamaophthalmol.2014.1405), incorrect information appeared. The Snellen equivalents provided in the fourth and fifth sentences of the fourth paragraph, which read “At the time of CNV detection, this latter cohort had better median visual acuities that differed from the standard ca



0

Reversal of Toxic Manifestations of Chlorpromazine

from ArchOpht - 01 Oct 14

A, Patient receiving unsupervised chlorpromazine therapy presented with low vision and darkened skin of face and hands. B, Diffusely scattered star-shaped granular deposits were seen on cornea (arrowhead). C, Dirty-white anterior lenticular opacities seen (arrowhead). D, Resolution of pigmentation occurred following drug withdrawal.



0

Optical Coherence Tomography of a Cystic Retinal Tuft

from ArchOpht - 01 Oct 14

Cystic retinal tuft (CRT) is a developmental vitreoretinal abnormality found in 5% of autopsy eyes. Clinical examination reveals a focal, elevated gliotic lesion in the peripheral retina associated with vitreous traction (Figure, A and B). Histopathological analysis demonstrates a dome-shaped area with internal microcysts, glial cell proliferation, outer retinal degeneration, and photoreceptor loss. Optical coherence tomography reveals a similar configuration with separation of the retina from t



0

Multiple Serous Retinal Detachments Seen on Wide-Field Imaging in a Patient With Sympathetic Ophthalmia

from ArchOpht - 01 Oct 14

A 20-year-old healthy patient with a history of corneal perforation from chronic herpetic disease in the left eye presented with decreased vision in the right eye. Wide-field fluorescein angiography showed punctate areas of leakage and multiple lobular serous retinal detachments in the posterior pole of the right eye (A), consistent with a diagnosis of sympathetic ophthalmia; the subretinal fluid had resolved 2 months later, after treatment with oral prednisone and initiation of mycophenolate mo



0

Combined Branch Retinal Artery and Vein Occlusion in Hyperhomocysteinemia

from ArchOpht - 01 Oct 14

A healthy man in his late 30s experienced sudden visual loss and presented with an extremely rare combination of branch retinal artery (black arrowhead) and vein (white arrowhead) occlusion that progressed to neovascular glaucoma. Blood workup revealed hyperhomocysteinemia (homocysteine level, 52 µmol/L [to convert to milligrams per liter, divide by 7.397]).



0

JAMA Ophthalmology

from ArchOpht - 01 Oct 14

Mission Statement: To be the indispensable source of ophthalmic knowledge by promptly publishing innovative, clinically relevant research through consistent and authoritative peer review and;thereby, to be the first choice of authors for their important manuscripts.


 

203 items Page 1 of 9 1 2 3 4 5 6 7 8 9 >>

    Search

    Categories

    Keyword cloud

    Abstract back Blood brain breast cardiac cardiovascular change chronic Coupons diabetes dog Ebola England genetic infection Lancet lung Oct Pain Reviews Screening supplied UK Volume

    Top news voters

    dr_el_taweel1 vote
    magy.sobhy821 vote

    © 2014 BMJ Publishing Group Ltd . All rights reserved.