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“Granulomatosis With Polyangiitis (Wegener's)” for “Wegener Granulomatosis” Dermatology Journals Should Also Adopt the Alternative Name Granulomatosis With Polyangiitis (Wegener's)

from ArchDerm - 01 May 13

Recently, Galve et al reported a quiz case describing a patient with grouped papules and vesicles indicating “Wegener granulomatosis.” This is the opportunity to comment on the name given to this disease. Indeed, we have no doubt that ethical considerations should be introduced into medical nomenclature and nosology, particularly for eponyms—a name given to a disease or condition, semiological signs, or anatomical area based on the name of a person to honor his or her finding.

Medicamina Faciei Femineae : Roman Skin Care

from ArchDerm - 01 May 13

A Female Pioneer—Doubly Recognized

from ArchDerm - 01 May 13

Eponyms abound in dermatology, giving recognition to those who have advanced the specialty. Behind eponyms, there are often tales about physicians, patients, and the times in which they lived.

A Maroon Plaque in an Infant

from ArchDerm - 01 May 13

Large congenital masses appropriately raise clinical concern, especially when they do not present with the classic appearance, thus requiring consideration of broad differential diagnostic categories prior to conclusive diagnosis. We discuss analysis and treatment of a vascular lesion most closely resembling a fibrous hamartoma of infancy (FHI).

A Palpable Erythematous Cord Over the Trunk in a Patient With Systemic Lupus Erythematosus—Diagnosis

from ArchDerm - 01 May 13

A Palpable Erythematous Cord Over the Trunk in a Patient With Systemic Lupus Erythematosus—Quiz Case

from ArchDerm - 01 May 13

A Rapidly Enlarging Nodule on the Dorsal Aspect of the Nose—Diagnosis

from ArchDerm - 01 May 13

A Rapidly Enlarging Nodule on the Dorsal Aspect of the Nose—Quiz Case

from ArchDerm - 01 May 13

About This Journal

from ArchDerm - 01 May 13

Association of Androgenetic Alopecia With Mortality From Diabetes Mellitus and Heart Disease Androgenetic Alopecia and Mortality

from ArchDerm - 01 May 13

ImportanceIdentifying predictors of mortality from diabetes mellitus (DM) and heart disease can help shape treatment strategies. Presence of androgenetic alopecia (AGA) might be such a predictor.ObjectiveTo determine whether the presence of AGA is associated with an elevated rate of mortality from DM and heart disease in both sexes after adjustment for potential confounders.DesignA population-based prospective cohort study.SettingCommunity-based integrated screening in Taiwan.ParticipantsA total

Dasatinib-Induced Leukotrichia in a Patient With Chronic Myelogenous Leukemia

from ArchDerm - 01 May 13

Dasatinib, a thiazole carboxamide derivative, is a second-generation tyrosine kinase inhibitor (TKI), similar in structure to imatinib, that is used for the treatment of chronic myelogenous leukemia (CML). We report a case of extensive dasatinib-induced leukotrichia in a patient with refractory CML.

Diffuse Umbilicated Vesicles in a Critically Ill Child

from ArchDerm - 01 May 13

Methicillin-resistant Staphylococcus aureus (MRSA) septicemia can produce disseminated skin lesions, but a vesicular eruption is not a well-recognized presentation of this infection.

Effect of Store and Forward Teledermatology on Quality of Life A Randomized Controlled Trial Store and Forward Teledermatology

from ArchDerm - 01 May 13

ImportanceAlthough research on quality of life and dermatologic conditions is well represented in the literature, information on teledermatology's effect on quality of life is virtually absent.ObjectiveTo determine the effect of store and forward teledermatology on quality of life.DesignTwo-site, parallel-group, superiority randomized controlled trial.SettingDermatology clinics and affiliated sites of primary care at 2 US Department of Veterans Affairs medical facilities.ParticipantsPatients bei

Eruptive Melanocytic Nevi in a Patient Undergoing Treatment With Sunitinib

from ArchDerm - 01 May 13

The onset of eruptive melanocytic nevi (EMN) is an uncommon phenomenon characterized by sudden onset of multiple melanocytic nevi (MN). This phenomenon has been linked primarily to bullous diseases or conditions of immunosuppression. A newly described cause of EMN is the multikinase inhibitor sorafenib and its relationship to inhibition of the BRAFV600E mutation (Table).

Facial Stigmata and Their Powerful Effects in Literature and Life

from ArchDerm - 01 May 13

Factors Predictive of Recurrence and Death From Cutaneous Squamous Cell Carcinoma A 10-Year, Single-Institution Cohort Study Recurrence and Death From CSCC

from ArchDerm - 01 May 13

ImportanceAlthough most cases of cutaneous squamous cell carcinoma (CSCC) are easily cured with surgery or ablation, a subset of these tumors recur, metastasize, and cause death. We conducted the largest study of CSCC outcomes since 1968.ObjectiveTo identify risk factors independently associated with poor outcomes in primary CSCC.DesignA 10-year retrospective cohort study.SettingAn academic hospital in Boston.ParticipantsNine hundred eighty-five patients with 1832 tumors.Main Outcomes and Measur

Flexural Agminated Eruptive Nevi in Langerhans Cell Histiocytosis

from ArchDerm - 01 May 13

Langerhans cell histiocytosis (LCH) is a multisystemic disease of childhood characterized by abnormal clonal proliferation of Langerhans cells, with skin lesions often involving flexural areas. We report 2 cases of eruptive nevi seen in skin folds of children with LCH.

Foreign-Body Reaction to Wound Seal

from ArchDerm - 01 May 13

Wound Seal (Biolife LLC) is a product composed of a hydrophilic polymer and potassium iron oxyacid salt that aids in hemostasis in wounds that are left to heal by secondary intention. We report a foreign-body reaction that results in the dermis following its use.

Harnessing Hedgehog for the Treatment of Basal Cell Carcinoma Hedgehog for Treatment of Basal Cell Carcinoma

from ArchDerm - 01 May 13

Vismodegib, a first-in-class small-molecule hedgehog pathway inhibitor, was approved by the Food and Drug Administration in January 2012 for the treatment of metastatic and locally advanced basal cell carcinoma (BCC). The commentary by Wysong et al in this issue of JAMA Dermatology highlights the poor response of metastatic BCC to conventional forms of therapy, making hedgehog pathway antagonists an important addition to the therapeutic armamentarium for this rare but deadly type of BCC.

Hereditary Benign Telangiectasia: Punctate Telangiectasia Surrounded by Anemic Halo

from ArchDerm - 01 May 13

Hereditary benign telangiectasia (HBT) is a primary telangiectatic disorder, characterized by the presence of telangiectasias with different morphological features (lineal, punctiform, arborescent, reticulated, or in plaques) on the face, neck, upper trunk, and extremities. The mucosae are not affected, and there is no systemic involvement. Because it is an autosomal dominant disorder, lesions are usually present in several members of a single family.

Immediate Successful Treatment of Argyria With a Single Pass of Multiple Q-Switched Laser Wavelengths

from ArchDerm - 01 May 13

Argyria is a mucocutaneous discoloration caused by exposure to airborne silver particles or long-term ingestion of ionized silver solutions. It is intriguing in the sense that it creates a profound skin color change. It is known that ionized or colloidal silver particles have the highest affinity for dermal elastic fibers and eccrine glands. Once the colloidal silver particles deposit around eccrine glands, they are indeed colorless. It is in the dermal matrix where the silver particles combine

In This Issue of JAMA Dermatology

from ArchDerm - 01 May 13

Inconsistency in Clinical Measurements Can Be Improved Through Training Comment on “Standardizing Training for Psoriasis Measures” Inconsistency Improved Through Training

from ArchDerm - 01 May 13

Neutrophilic Dermatosis After Azathioprine Exposure Neutrophilic Dermatosis and Azathioprine Exposure

from ArchDerm - 01 May 13

ImportanceAzathioprine hypersensitivity syndrome can present clinically and histopathologically like Sweet syndrome. Shared clinical features include fever, constitutional symptoms, prompt response to systemic corticosteroid therapy, neutrophilia, and abrupt onset of erythematous cutaneous lesions. Histologically, both azathioprine hypersensitivity syndrome and Sweet syndrome are rich in neutrophils.ObservationsAn 81-year-old woman with Crohn disease presented with fever and an acute eruption of

Nonmelanoma Skin Cancer in Organ Transplant Recipients: Increase Without Delay After Transplant and Subsequent Acceleration

from ArchDerm - 01 May 13

Organ transplant recipients (OTRs) have a 60- to 250-fold increased risk for cutaneous squamous cell carcinoma (SCC) and a 10-fold increased risk for basal cell carcinoma (BCC). It is still unclear, however, how fast after transplant these tumors arise. To develop risk-adjusted clinical follow-up in OTRs, we investigated the incidence of first and subsequent nonmelanoma skin cancers (NMSCs) in OTRs.