• Find us on Facebook
  • Follow BMJ OnExamination on Twitter

Latest News

Like this article?

Click vote now


0

Yaws Renewed Hope for Eradication

from ArchDerm - 01 Sep 14

Yaws is the most common and severe of the endemic treponematoses (ie, yaws, begel, and pinta). This chronic, neglected tropical disease is caused by a noncultivable, spiral-shaped bacterium that is very closely related (approximately?99.8%) to the agent of venereal syphilis, Treponema pallidum subspecies pallidum (Table). Yaws primarily affects children ages 2 to 15 years who live in poor rural communities in forested tropical areas of Africa, Southeast Asia, and the Pacific Islands. Infection w



0

The Value of Our Care

from ArchDerm - 01 Sep 14

The significance of the study by Kirby et al is its attention to costs. As physicians, we are often so preoccupied with treating patients and focusing on diseases that we do not consider the costs that we are incurring and therefore the value of our care. Health care spending in the United States was approximately 17.9% of the gross domestic product (GDP) in 2012 and has been on the rise for many years. The per-capita health expenditures grew 3.2% in 2012. Although health care expenditures have



0

Health Care Utilization Patterns and Costs for Patients With Hidradenitis Suppurativa

from ArchDerm - 01 Sep 14

ImportanceHidradenitis suppurativa (HS) is a chronic cutaneous disease with acutely painful flares that require appropriate and timely treatment.ObjectiveTo assess how individuals with HS utilize medical care, especially emergency department (ED) care, a high-cost setting, and to describe the health care costs for this group.Design, Setting, and ParticipantsCohort cost-identification study of 150?493 individuals with claims from the MarketScan medical claims database. Patients with claims for HS



0

Global Burden of Skin Disease as Reflected in Cochrane Database of Systematic Reviews

from ArchDerm - 01 Sep 14

ImportanceResearch prioritization should be guided by impact of disease.ObjectiveTo determine whether systematic reviews and protocol topics in Cochrane Database of Systematic Reviews (CDSR) reflect disease burden, measured by disability-adjusted life years (DALYs) from the Global Burden of Disease (GBD) 2010 project.Design, Setting, and ParticipantsTwo investigators independently assessed 15 skin conditions in the CDSR for systematic review and protocol representation from November 1, 2013, to



0

Diagnostic Usefulness of a Peribulbar Eosinophilic Infiltrate in Alopecia Areata

from ArchDerm - 01 Sep 14

ImportanceThe histopathologic diagnosis of alopecia areata (AA) may be difficult in the chronic stage in which the presence of a peribulbar lymphocytic infiltrate is not definite. An eosinophilic infiltrate has been reported as a relatively common histopathologic finding and a helpful diagnostic feature in AA.ObjectiveTo investigate the frequency and diagnostic usefulness of an eosinophilic infiltrate around the hair bulbs or within the fibrous tracts during the chronic stage of AA.Design, Setti



0

Hypertension, Antihypertensive Medication Use, and Risk of Psoriasis

from ArchDerm - 01 Sep 14

ImportanceIndividuals with psoriasis have an elevated risk of hypertension, and antihypertensive medications, especially ß-blockers, have been linked to psoriasis development. However, the association of prior existing hypertension and antihypertensive medications with risk of incident psoriasis has not been assessed using prospective data.ObjectiveTo evaluate the association of hypertension and antihypertensive medications with risk of psoriasis.Design, Setting, and ParticipantsWe performed a p



0

Infrared Thermography to Assess Proliferation and Involution of Infantile Hemangiomas A Prospective Cohort Study

from ArchDerm - 01 Sep 14

ImportanceInfantile hemangiomas (IHs) are common benign tumors of infancy that have the potential to interfere with vital organ function and cause permanent disfigurement. Currently, few objective and validated measures exist to assess IHs.ObjectiveTo determine the utility of infrared thermography in assessing and monitoring the growth of IHs.Design, Setting, and ParticipantsIn a prospective cohort study conducted at an outpatient dermatology clinic of a tertiary care hospital between February 2



0

Two Different Scenarios of Squamous Cell Carcinoma Within Advanced Basal Cell Carcinomas Cases Illustrating the Importance of Serial Biopsy During Vismodegib Usage

from ArchDerm - 01 Sep 14

ImportanceVismodegib is a Hedgehog signaling pathway inhibitor recently approved by the US Food and Drug Administration for advanced basal cell carcinoma. We present 2 cases of clinically significant squamous cell carcinoma within the tumor bed of locally advanced basal cell carcinoma found during vismodegib treatment.ObservationsThe first case is that of a patient with locally advanced basal cell carcinoma responsive to vismodegib but with an enlarging papule within the tumor bed. On biopsy, th



0

Acquired Bilateral Telangiectatic Macules A Distinct Clinical Entity

from ArchDerm - 01 Sep 14

ImportanceWe evaluated 13 distinct patients with multiple telangiectatic pigmented macules confined mostly to the upper arms to determine if the clinical and histopathological features of these cases might represent a specific clinical entity.ObservationsWe retrospectively investigated the clinical, histopathologic, and immunohistochemical features of 13 patients with multiple telangiectatic pigmented macules on the upper arms who presented between January 2003 and December 2012. Epidermal pigme



0

Congenital Volkmann Syndrome and Aplasia Cutis of the Forearm A Challenging Differential Diagnosis

from ArchDerm - 01 Sep 14

ImportanceDifferential diagnosis between congenital Volkmann ischemic contracture (CVIC) and unilateral aplasia cutis congenita (ACC) type VII of the forearm presents a clinical challenge. Both diseases share the same clinical presentation characterized by a stellate ulceration over the upper extremities and reported association with neuromuscular defects, but the diagnostic criteria to differentiate these 2 entities remain unclear.ObservationsA newborn girl presented with an ulceration of the l



0

Mycobacterium mucogenicum Infection Following Dacryocystorhinostomy and Crawford Tube Placement

from ArchDerm - 01 Sep 14

ImportanceNontuberculous mycobacterial infections of the skin can be seen in cases of immunosuppression and/or traumatic implantation of contaminated objects. Surgical settings with appropriate sterilization techniques have been immune to these types of infections. We report a case of nosocomially derived infection from a sterile procedure.ObservationsA woman in her 70s presented with a facial lesion after an ophthalmologic procedure that was discovered to be a nontuberculous mycobacterial infec



0

Blue-Gray Mucocutaneous Discoloration A New Adverse Effect of Ezogabine

from ArchDerm - 01 Sep 14

ImportanceMany drugs have been reported to induce skin and/or mucous membrane discoloration. Ezogabine (retigabine) was recently approved as an add-on drug for the treatment of partial seizures in adults with epilepsy. Mucocutaneous discoloration induced by antiepileptic drugs in general and ezogabine in particular has not been previously reported.ObservationsTwo patients who had received multiple antiepileptic drugs for several years presented with a blue-gray skin dyspigmentation that was most



0

A Limited Form of Proteus Syndrome With Bilateral Plantar Cerebriform Collagenomas and Varicose Veins Secondary to a Mosaic AKT1 Mutation

from ArchDerm - 01 Sep 14

ImportanceProteus syndrome is an extremely rare disorder of mosaic postnatal overgrowth affecting multiple tissues including bone, soft tissue, and skin. It typically manifests in early childhood with asymmetric and progressive skeletal overgrowth that leads to severe distortion of the skeleton and disability. The genetic basis has recently been identified as a somatic activating mutation in the AKT1 gene, which encodes an enzyme mediating cell proliferation and apoptosis.ObservationsWe present



0

Confocal Microscopy–Guided Laser Ablation for Superficial and Early Nodular Basal Cell Carcinoma A Promising Surgical Alternative for Superficial Skin Cancers

from ArchDerm - 01 Sep 14

ImportanceLaser ablation is a rapid and minimally invasive approach for the treatment of superficial skin cancers, but efficacy and reliability vary owing to lack of histologic margin control. High-resolution reflectance confocal microscopy (RCM) may offer a means for examining margins directly on the patient.ObservationsWe report successful elimination of superficial and early nodular basal cell carcinoma (BCC) in 2 cases using RCM imaging to guide Er:YAG laser ablation. Three-dimensional (3D)








0

Overview Photography and Short-term Mole Monitoring in Patients Taking a BRAF Inhibitor

from ArchDerm - 01 Sep 14

Patients taking BRAF inhibitors develop new primary melanomas and nevi. Many of these neoplasms are BRAF wild-type, which may be due to the paradoxical activation of the RAF/MEK/ERK pathway via an alternative driver mutation, similar to the mechanism involved in inducing the development of squamous cell carcinomas in these patients. In addition, some nevi in these individuals involute, and many of these involuting lesions harbor a BRAFV600E (OMIM *164757) mutation.



0

Portable Shade Structure Use at a Youth Soccer Camp

from ArchDerm - 01 Sep 14

More than 3 million nonmelanoma skin cancers (NMSCs) are diagnosed annually in the United States. The incidence of malignant melanoma (MM) has increased annually by 2.4%. Open field activities in youth are a major source of sun exposure, which leads to skin cancer later in life. Few studies exist on the use of shade structures in open field sports, particularly soccer. In this pilot study, we assess the rate of use of portable shade structures among soccer-playing youths.



0

An Oral Phosphodiesterase Inhibitor (Apremilast) for Inflammatory Rosacea in Adults: A Pilot Study

from ArchDerm - 01 Sep 14

Rosacea is a chronic skin disorder characterized by facial flushing, persistent erythema, telangiectasias, and inflammatory papules and pustules. In addition to the physical manifestations, rosacea may contribute to lower self-esteem, thereby having significant psychosocial implications. Some patients do not respond to conventional treatments for rosacea or are unable to tolerate the adverse effects; therefore, effective new therapies are needed. We sought to investigate the safety and efficacy



0

Psoriasis Provoked or Exacerbated by Medications Identifying Culprit Drugs

from ArchDerm - 01 Sep 14

A critical practice gap exists in identifying the causes of psoriasis flares, especially medication-related causes. Some physicians may not consistently examine medications for their contribution to psoriasis flares. However, a careful consideration of the role of medications in psoriasis exacerbation may improve long-term psoriasis control.



0

Tumoral Bacillary Angiomatosis in a Child With Human Immunodeficiency Virus

from ArchDerm - 01 Sep 14

Bacillary angiomatosis (BA) is a life-threatening infection caused by gram-negative organisms of the genus Bartonella that can be cured with appropriate therapy. The clinical manifestations of this infection are diverse, and a high index of suspicion and histopathologic analysis are often required to make the diagnosis.


 

217 items Page 1 of 9 1 2 3 4 5 6 7 8 9 >>

    Search

    Categories

    Keyword cloud

    Abstract Aug back blood brain breast Cardiac cardiovascular change chronic Coupons Depression diabetes dog Ebola great Lancet lung Myocardial pain Prevalence Reviews Sep supplied weight

    Top news voters


    © 2014 BMJ Publishing Group Ltd . All rights reserved.